Biotin and derivatives
Medchemexpress LLC DBCO-biotin | 1418217-95-4 | MFCD22380751 | 98.5% | 502.63 g·mol⁻1 | C28H30N4O3S | 10MG
DBCO-Biotin is a bifunctional click-chemistry reagent that links a dibenzocyclooctyne (DBCO) reactive moiety to a biotin affinity tag, enabling copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) for bioconjugation and probe development. Supplied as a high-purity solid for laboratory research, it is commonly used in bioconjugation, affinity enrichment, and linker synthesis applications.
- Enables copper-free click chemistry via DBCO-mediated SPAAC.
- Provides a biotin tag for affinity capture and detection.
- High purity suitable for sensitive bioconjugation workflows.
- Available in small mg-scale quantities for research use.
- Stable when stored under recommended conditions; consult safety data for handling.
Apexbio Technology LLC 5-Carboxyfluorescein diacetate N-succinimidyl ester 150206-05-6 10mg
5-Carboxyfluorescein diacetate N-succinimidyl ester (CAS 150206-05-6) is a fluorescent cell-permeable dye It is designed to enable stable cell labeling by facilitating intracellular conversion and covalent attachment to cellular amines 5-Carboxyfluorescein diacetate N-succinimidyl ester exerts its activity through membrane permeation intracellular esterase-mediated cleavage of acetate groups and subsequent covalent coupling to intracellular targets resulting in persistent fluorescence through cell division Based on these properties 5-Carboxyfluorescein diacetate N-succinimidyl ester holds research potential in tracking lymphocyte migration analyzing cell proliferation and investigating cell dynamics and interactions in various in vitro and in vivo experimental models
Medchemexpress LLC Biotin/KLH | 1 MG
Biotin/KLH is an antigen-adjuvant conjugate composed of Biotin and Keyhole Limpet Hemocyanin (KLH). This conjugate is designed to enhance the production of antigen-specific antibodies in vaccine models by conjugating the antigen with a protein adjuvant. It maintains protein folding, does not disrupt major epitopes, and can improve cross-presentation and the generation of antigen-specific T cells.
- Enhances the production of antigen-specific antibodies in vaccine models.
- Does not affect protein folding or disrupt major epitopes.
- Can enhance cross-presentation and the generation of antigen-specific T cells.
Medchemexpress LLC Biotin-PFP ester | 120550-35-8 | 97.0% | 1 G
Biotin-PFP ester is a biotinylated pentafluorophenyl (PFP) ester reagent used as an alkyl/ether-based PROTAC linker for the synthesis of PROTAC molecules. It provides an activated ester for coupling to amine-containing ligands and a biotin affinity tag for purification or detection.
- Provides a biotin handle for affinity capture and detection.
- Features a PFP-activated ester for efficient coupling to amine-containing ligands.
- Suitable as an alkyl/ether-based linker in PROTAC synthesis workflows.
- Offered in multiple laboratory-scale pack sizes for convenient use.
![Medchemexpress LLC Succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate | 158913-22-5 | MFCD00083163 | 98.1% | 425.52 | C18H23N3O5S2 | 500MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000238859.png-250.jpg)
Medchemexpress LLC Succinimidyl 6-[3-(2-pyridyldithio)propionamido]hexanoate | 158913-22-5 | MFCD00083163 | 98.1% | 425.52 | C18H23N3O5S2 | 500MG
SPDP-C6-NHS ester is an alkyl/ether-based PROTAC linker that features an NHS-activated ester for amine coupling and a pyridyldisulfide moiety for disulfide conjugation. Supplied as a white to off-white solid, it is used in conjugation chemistry and the synthesis of PROTACs and related bifunctional molecules.
- Alkyl/ether-based PROTAC linker with an NHS activated ester.
- Contains a pyridyldisulfide group for disulfide bond formation.
- High purity: 98.1%.
- Molecular formula C18H23N3O5S2; molecular weight 425.52.
- Soluble in DMSO at 50 mg/mL; ultrasonic treatment recommended.
- Store powder at -20°C for long term; store solutions at -80°C for short term.
- Available in small-scale solid quantities for research use.
Medchemexpress LLC Biotin-Gastrin Releasing Peptide, human TFA | 3085.67 | 25 MG
Biotin-Gastrin Releasing Peptide, human TFA is a biotinylated gastrin releasing peptide (GRP). Gastrin-releasing peptide (GRP) is a neuropeptide known for its growth-stimulatory and tumorigenic properties.
- Biotinylated gastrin releasing peptide (GRP)
- Neuropeptide with growth-stimulatory properties
- Relevant for cancer and neurological disease research
- Related to GPCR/G protein and Bombesin Receptor studies
Medchemexpress LLC MeCY5-NHS ester triethylamine | 00-00-0 | 95.3% | C42H56N4O10S2 | 10MG
The triethylamine salt of a Cy5-family N-hydroxysuccinimide (NHS) ester for covalent fluorescent labeling of biomolecules. It reacts with primary amines on proteins, peptides, and oligonucleotides to form stable amide linkages, enabling far-red fluorescence detection in imaging and biochemical assays. The reagent is supplied in research-scale vials for conjugation workflows.
- Reacts with primary amines to form stable amide bonds.
- Suitable for labeling proteins, peptides, and oligonucleotides.
- Cy5-family fluorophore for far-red detection.
- Supplied as a triethylamine salt for handling and solubility.
- Available in small pack sizes for research use.
- Purity 95.3%.
Medchemexpress LLC Mal-PEG24-NHS ester | 2226733-37-3 | MFCD11041160 | 95.0% | C62H111N3O31 | 10MG
Mal-PEG24-NHS ester is a polyethylene glycol (PEG)-based bifunctional linker bearing a maleimide and an N-hydroxysuccinimide (NHS) ester. It enables thiol-to-maleimide and amine-to-NHS conjugation for assembly of PROTACs and other bioconjugates; supplied as a colorless to light-yellow oil with high purity and good aqueous solubility.
- Enables thiol and amine conjugation via maleimide and NHS ester chemistry.
- Long PEG24 spacer increases solubility and reduces steric hindrance.
- High purity supports reliable reaction performance.
- High aqueous solubility simplifies handling and formulation.
- Suitable for PROTAC synthesis and general bioconjugation workflows.