Biotin and derivatives
![Medchemexpress LLC Carbonic acid, 1-[4-[(16-azido-PEG3)oxy]-5-methoxy-2-nitrophenyl]ethyl 2,5-dioxo-pyrrolidinyl ester | 1802907-96-5 | MFCD29052189 | 98.7% | 640.60 g/mol | C26H36N6O13 | 50 MG](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000280727.png-250.jpg)
Medchemexpress LLC Carbonic acid, 1-[4-[(16-azido-PEG3)oxy]-5-methoxy-2-nitrophenyl]ethyl 2,5-dioxo-pyrrolidinyl ester | 1802907-96-5 | MFCD29052189 | 98.7% | 640.60 g/mol | C26H36N6O13 | 50 MG
PC Azido-PEG3-NHS carbonate ester is a photocleavable azido-PEG3 NHS carbonate linker for labeling primary amines on proteins, amine-modified oligonucleotides, and other amine-containing molecules. It combines an NHS carbonate reactive group with an azide handle and a photocleavable moiety to enable covalent labeling and light-triggered release. Supplied as a colorless to light-yellow oil for research use; follow manufacturer storage recommendations.
Medchemexpress LLC N-succinimidyl-3-(2-pyridyldithio)butyrate | 107348-47-0 | MFCD28398150 | 98.3% | 326.4 g/mol | C13H14N2O4S2 | 1 G
PPC-NHS ester (N-succinimidyl-3-(2-pyridyldithio)butyrate, CAS 107348-47-0) is an NHS-activated cleavable linker reagent used for conjugating small molecules to proteins and antibodies. It reacts with primary amines to form stable amide bonds and contains a pyridyldisulfide moiety that enables controlled cleavage under reducing conditions, making it suitable for antibody-drug conjugate synthesis and general bioconjugation.
- Reacts with primary amines to form stable amide bonds.
- Contains a pyridyldisulfide cleavable linkage for controlled release under reducing conditions.
- High purity suitable for conjugation workflows (≈98.3%).
- Compatible with common aqueous and organic conjugation conditions.
Sigma Aldrich Fine Chemicals Biosciences (+)-Biotin N-hydroxysuccinimide ester >=98% (HPLC), powder | 35013-72-0 | MFCD00078531 | 25MG
(+)-Biotin N-hydroxysuccinimide ester >=98% (HPLC), powder | Purity: >=98% (HPLC) | Mol Wt: 341.38 | 35013-72-0 | MFCD00078531 | 25MG
Medchemexpress LLC DBCO-biotin | 1418217-95-4 | MFCD22380751 | 98.5% | 502.63 | C28H30N4O3S | 50MG
DBCO-Biotin is an alkyl chain-based PROTAC linker and click-chemistry reagent that contains a dibenzocyclooctyne (DBCO) moiety conjugated to biotin, enabling copper-free strain-promoted alkyne-azide cycloaddition (SPAAC) with azide-containing molecules. Supplied as a white to off-white solid, it is used for biotinylation, conjugation, and PROTAC synthesis in chemical biology applications.
- High purity of 98.5%.
- Molecular weight 502.63 g/mol.
- Molecular formula C28H30N4O3S.
- Soluble in DMSO at 31.25 mg/mL (62.17 mM).
- Store protected from light under inert gas; solid recommended at -20°C.
- Packaged as 50 mg vial.
- Enables copper-free click conjugation via SPAAC.
Medchemexpress LLC CD79B Human Biotin 100ug
Recombinant human CD79B (extracellular residues Ala29-Asp159) produced in HEK293 cells and enzymatically biotinylated via an Avi tag. The construct includes a C-terminal His-Avi fusion, is >95% pure, and migrates ~35-45 kDa on SDS-PAGE due to glycosylation. Supplied with storage and reconstitution guidance for use in immobilization and binding assays.
- Site-specific biotinylation for consistent immobilization.
- C-terminal His-Avi tag for purification and controlled biotinylation.
- Mammalian expression preserves native glycosylation and folding.
- High purity suitable for ELISA, SPR/BLI, and flow cytometry.
- Storage and reconstitution recommendations to maintain activity.
Apexbio Technology LLC Sulfo-NHS-SS-11-Biotin 1g
Sulfo-NHS-SS-11-Biotin is an amine-reactive water-soluble biotinylation reagent containing an N-hydroxysulfosuccinimide (Sulfo-NHS) active ester group and a cleavable disulfide bond The Sulfo-NHS moiety reacts specifically with primary amines in proteins peptides or other biomolecules forming stable amide linkages This reagent introduces a disulfide-containing spacer arm enabling subsequent selective cleavage under reducing conditions for release of biotinylated molecules It is commonly employed in affinity chromatography immunoprecipitation experiments cell surface protein labeling and target identification allowing isolation purification or detection of biomolecules through streptavidin or avidin affinity interactions